A client with heart failure reports a weight gain of 3 lb over 2 days and increased ankle swelling. Which medication's dosage adjustment does the nurse anticipate?

Study for the UWorld Pharmacology Test. Use flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

In the setting of heart failure, the observed symptoms of weight gain and increased ankle swelling suggest fluid retention, which could indicate worsening heart failure. Bumetanide is a loop diuretic commonly used to manage fluid overload in patients with heart failure. When a patient exhibits signs of excessive fluid retention, an increase in the dosage of bumetanide may be warranted to enhance diuresis and alleviate the symptoms caused by fluid accumulation, such as edema and weight gain.

Bumetanide works by inhibiting sodium and chloride reabsorption in the loop of Henle, leading to increased urine output and decreased fluid volume. This adjustment can help manage the client’s condition and improve their overall clinical status.

In contrast, other medications listed, such as candesartan (an angiotensin receptor blocker), carvedilol (a beta-blocker), and isosorbide (a nitrate), do not primarily act as diuretics and are not the first line of treatment for addressing immediate fluid retention issues in heart failure. Their dosages might be optimized for other reasons, such as blood pressure control or heart rate management, but they do not directly address the acute need for fluid removal in this situation. Thus, the appropriate course of action in this case would

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