What are the main therapeutic uses of Metformin?

Study for the UWorld Pharmacology Test. Use flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Metformin is primarily used in the management of type 2 diabetes mellitus due to its ability to improve insulin sensitivity, reduce hepatic glucose production, and enhance peripheral glucose uptake. It is particularly effective in lowering blood sugar levels and is often the first-line medication prescribed for patients with this condition.

In addition to its role in controlling blood glucose levels, metformin has been found to contribute to weight management. Many patients with type 2 diabetes struggle with obesity, and metformin's effects include promoting weight loss or preventing weight gain, which is a significant benefit for these individuals.

The other options listed do not align with the primary therapeutic indications for metformin. It is not used in the management of type 1 diabetes, which requires insulin therapy, nor is it indicated for controlling hypertension or hyperlipidemia, which are treated with other classes of medications specifically designed for those conditions.

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