What essential intervention must be performed before starting atorvastatin therapy?

Study for the UWorld Pharmacology Test. Use flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Before initiating atorvastatin therapy, it is crucial to monitor liver function tests. Atorvastatin is a member of the statin class of medications, which are primarily used to lower cholesterol levels and reduce the risk of cardiovascular disease. One of the significant concerns with statin use is the potential for liver enzyme elevation, which can indicate hepatotoxicity.

Prior to starting atorvastatin, baseline liver function tests should be conducted to assess the patient's hepatic status. This is important as it allows for the identification of any pre-existing liver conditions that could be exacerbated by statin therapy. Regular monitoring of liver enzymes during treatment is also recommended to ensure that the liver remains healthy throughout the course of therapy. If there is a significant elevation in liver enzymes, it may necessitate discontinuation or adjustment of the medication.

The intervention of monitoring liver function tests is a key aspect of safely managing a patient’s treatment with atorvastatin, ensuring that any potential adverse effects on the liver can be promptly identified and addressed.

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