What expected therapeutic response should a nurse observe in a client taking levothyroxine?

The expected therapeutic response in a client taking levothyroxine is an apical heart rate of 88 beats per minute. Levothyroxine is a synthetic form of the thyroid hormone thyroxine (T4), which is used to treat hypothyroidism. The aim of treatment is to normalize metabolic activity and restore normal physiological functions.

In patients with hypothyroidism, there is usually a reduction in metabolic rate, which can result in a slower heart rate (bradycardia). When treated with levothyroxine, the metabolic rate increases, leading to the resolution of symptoms associated with hypothyroidism, including bradycardia. An apical heart rate of 88 beats per minute indicates a normalized heart rate, which is consistent with a therapeutic response to levothyroxine.

The other options do not align with the therapeutic goals of levothyroxine treatment. Cool and dry skin would be associated with hypothyroidism, not treatment. Slight weight gain could occur if the medication does not adequately replace thyroid hormones, while rapid weight gain would be contrary to the expected outcome of achieving metabolic balance and weight management. Thus, observing a stable and appropriate heart rate like 88 beats per minute indicates that the treatment is effective in restoring normal thyroid