What is one of the therapeutic uses of beta-blockers?

Study for the UWorld Pharmacology Test. Use flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Beta-blockers are primarily utilized in the management of hypertension due to their ability to reduce heart rate and decrease cardiac output, ultimately leading to lower blood pressure. By blocking the beta-adrenergic receptors, these medications inhibit the effects of adrenaline (epinephrine) on the cardiovascular system, resulting in vasodilation and improved blood flow. This pharmacological action makes beta-blockers effective for treating high blood pressure and for reducing the risk of related cardiovascular complications, such as myocardial infarction and stroke.

While beta-blockers may have other uses in different contexts, hypertension management is a key and well-established therapeutic application. For instance, weight management is typically addressed through lifestyle changes or other medications, and thyroid hormone regulation usually involves different classes of drugs specifically targeting thyroid function. Anticoagulation refers to preventing blood clot formation, which is managed with anticoagulants rather than beta-blockers.

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