What is the reason for prescribing aspirin to patients with cardiovascular disease?

Study for the UWorld Pharmacology Test. Use flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Aspirin is prescribed to patients with cardiovascular disease primarily to prevent platelet aggregation and reduce the risk of thrombus formation. It accomplishes this by inhibiting the enzyme cyclooxygenase, which leads to a decrease in the production of thromboxane A2, a substance that promotes platelet activation and aggregation. By reducing platelet clumping, aspirin helps to maintain blood flow and decreases the likelihood of clot formation, thereby lowering the risk of heart attacks and strokes in at-risk patients. This antiplatelet effect is particularly beneficial for individuals with a history of cardiovascular events or those with risk factors for such events.

While aspirin does not directly influence blood pressure, cholesterol levels, or heart rate, its role in minimizing thrombus formation is critical in the management of cardiovascular disease.

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