What medication is commonly used to treat severe asthma exacerbations?

Study for the UWorld Pharmacology Test. Use flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Systemic corticosteroids are the preferred choice for treating severe asthma exacerbations due to their potent anti-inflammatory effects. During a severe exacerbation, the airways become inflamed and narrowed, making it difficult for patients to breathe. Systemic corticosteroids can reduce this inflammation quickly and effectively, leading to an improvement in airflow and respiratory function.

These medications work by inhibiting the production of inflammatory mediators and reducing the activity of immune cells involved in the inflammatory process. In contrast, leukotriene modifiers are typically used for long-term management of asthma and may not provide rapid relief during acute situations. Long-acting beta agonists are also used for maintenance therapy in asthma management, not for immediate treatment of exacerbations. Antihistamines primarily alleviate allergic symptoms and are not effective in addressing the underlying airway inflammation seen in asthma exacerbations. Therefore, the use of systemic corticosteroids is critical in managing severe asthma exacerbations to achieve prompt and effective control of symptoms.

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