What serum creatinine level necessitates immediate action for a client on lisinopril therapy?

Study for the UWorld Pharmacology Test. Use flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Serum creatinine level is a crucial indicator of kidney function, particularly for patients on medications such as lisinopril, which is an ACE inhibitor. An elevated serum creatinine level can suggest worsening renal function, which is a significant concern when a patient is being treated with an ACE inhibitor.

A serum creatinine level of 2.5 mg/dL is elevated and may indicate impairment in kidney function, which could potentially lead to complications such as acute kidney injury. This situation necessitates immediate attention, as continuing an ACE inhibitor like lisinopril in the presence of significant renal impairment could further aggravate the condition and increase the risk of toxicity. Therefore, the 2.5 mg/dL level specifically requires action to evaluate and potentially adjust the therapy to ensure patient safety.

On the other hand, a blood pressure of 129/80 mm Hg is within the typical range considered normal and does not indicate a need for urgent action. A heart rate of 100/min, while elevated, may not require immediate intervention related to renal function or lisinopril therapy, as it could be influenced by various factors. Lastly, a serum potassium level of 3.5 mEq/L is at the lower end of normal for potassium levels

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