Which herbal supplement is recommended to help synchronize the body to environmental time and alleviate jet lag?

Study for the UWorld Pharmacology Test. Use flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Melatonin is the correct choice for helping synchronize the body to environmental time and alleviating jet lag because it is a hormone that the body naturally produces in response to darkness, regulating the sleep-wake cycle. When traveling across time zones, the body’s internal clock can become misaligned with the local time, leading to feelings of fatigue and disorientation. Supplementing with melatonin can help signal to the body that it is time to sleep, aiding in the adjustment to a new time zone.

Other options like evening primrose, ginseng, and St. John's wort do not have a direct role in regulating sleep patterns or circadian rhythms. Evening primrose is often used for skin conditions and hormonal support, ginseng is typically associated with energy and stamina-boosting properties, and St. John's wort is mainly recognized for its potential to alleviate mild to moderate depression. None of these supplements effectively target the issue of jet lag and circadian synchronization in the same way that melatonin does.

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