Which medication is commonly used as an anticoagulant?

Study for the UWorld Pharmacology Test. Use flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Warfarin is commonly used as an anticoagulant because it acts by inhibiting the synthesis of vitamin K-dependent clotting factors in the liver, which are crucial for the coagulation cascade. By reducing the levels of these factors, Warfarin decreases the blood's ability to form clots, making it effective for preventing and treating thromboembolic events, such as deep vein thrombosis or pulmonary embolism.

The mechanism of action and the specific role of Warfarin in managing conditions at risk for thrombus formation highlight its significance as an anticoagulant. It is often monitored through INR (International Normalized Ratio) to ensure therapeutic levels are maintained and to avoid complications related to excessive bleeding or inadequate anticoagulation.

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