Which medication is often prescribed for hyperlipidemia?

Study for the UWorld Pharmacology Test. Use flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Statins are a class of medications primarily used to manage hyperlipidemia, which refers to elevated levels of lipids in the blood, particularly cholesterol. Statins work by inhibiting the enzyme HMG-CoA reductase, which plays a crucial role in the biosynthesis of cholesterol in the liver. By reducing cholesterol production, statins lead to decreased levels of low-density lipoprotein (LDL) cholesterol, often referred to as "bad" cholesterol, and can also contribute to an increase in high-density lipoprotein (HDL) cholesterol, or "good" cholesterol.

In addition to their primary function of lowering cholesterol levels, statins have been shown to have cardiovascular benefits, such as reducing the risk of heart attack and stroke. This dual action makes them a cornerstone in the treatment of patients with hyperlipidemia and those at risk for cardiovascular events.

Other classes of medications listed do serve important purposes in cardiovascular health but are not specifically indicated for the treatment of hyperlipidemia. For instance, beta-blockers primarily manage hypertension and other cardiac conditions, ACE inhibitors focus on hypertension and heart failure, and calcium channel blockers mainly treat hypertension and certain arrhythmias. Thus, statins distinctly stand out as the first-line choice for

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