Which of the following drugs is used in the management of congestive heart failure?

Study for the UWorld Pharmacology Test. Use flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Digoxin is used in the management of congestive heart failure (CHF) due to its ability to increase the force of cardiac contraction, which improves the efficiency of the heart in pumping blood. This positive inotropic effect is particularly beneficial in patients with heart failure, where the heart's ability to pump effectively is compromised. Additionally, digoxin helps to regulate heart rhythm and can be particularly effective in patients who also have atrial fibrillation, a common arrhythmia seen in heart failure patients.

Furosemide is a diuretic commonly used in the management of fluid overload associated with CHF but does not directly improve heart contractility. Metoprolol is a beta-blocker that can be used in heart failure to improve long-term outcomes by reducing heart rate and myocardial oxygen demand, but it primarily addresses heart rate and rhythm rather than directly enhancing contractility. Aspirin is an anti-inflammatory and antiplatelet medication, and while it may be used in patients with cardiovascular disease, it is not a treatment for CHF itself.

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