Which of the following statements regarding the use of warfarin is correct?

Regular INR monitoring is essential when using warfarin because it ensures that the medication is dosed safely and effectively. Warfarin is an anticoagulant that works by inhibiting vitamin K-dependent clotting factors, which requires precise dosing to maintain the International Normalized Ratio (INR) within a therapeutic range. Monitoring the INR helps healthcare providers adjust the dose based on how well the medication is controlling blood coagulation and to minimize the risk of bleeding or thromboembolic events.

Maintaining consistent INR levels requires awareness of diet, potential interactions with other medications, and changes in health status, all of which can affect how warfarin works in the body. For example, fluctuations in vitamin K intake, often found in leafy green vegetables, can significantly influence warfarin’s effectiveness, necessitating ongoing monitoring and dosage adjustments.

Other statements can lead to misconceptions about the management of patients on warfarin. Completely avoiding leafy greens is not necessary, but patients should maintain a consistent intake. Warfarin interacts with various medications, including antibiotics and over-the-counter drugs, which can alter its effectiveness, thus requiring careful management. Therefore, regular INR monitoring is a critical practice in the safe administration of warfarin.